Certificate of Analysis

 

Product Name: XL-184
Catalog Number: M1757
CAS Number: 849217-68-1

Physical and Chemical Properties
Formula: C28H24FN3O5
Molecular Weight: 501.51
Solubility: DMSO 70 mg/mL
Storage: 2-8°C, protect from light
Chemical Structure: XL-184 Structure
Analytical Data
QC Standard: 99.38%
H-NMR: Consistent with structure
Product Information
Description: XL184 is a small molecule inhibits multiple receptor tyrosine kinases, specifically MET and VEGFR2 with IC50 values of 0.035 and 1.8 nM for VEGFR2 and Met respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.