Certificate of Analysis

 

Product Name: WYE-125132
Catalog Number: M3556
CAS Number: 1144068-46-1

Physical and Chemical Properties
Formula: C27H33N7O4
Molecular Weight: 519.6
Solubility: DMSO 100 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: WYE-125132 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: WYE-125132 is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.