Certificate of Analysis

 

Catalog Number: M3130
Product Name: WHI-P154
CAS Number: 211555-04-3

Physical and Chemical Properties
Formula: C16H14BrN3O3
Molecular Weight: 376.2
Solubility: DMSO 60 mg/mL
Long-term Storage: at -20℃
Chemical Structure: WHI-P154 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.