Certificate of Analysis

 

Catalog Number: M3294
Product Name: VX-745
CAS Number: 209410-46-8

Physical and Chemical Properties
Formula: C19H9Cl2F2N3OS
Molecular Weight: 436.26
Solubility: DMSO 10 mg/mL
Long-term Storage: at -20℃
Chemical Structure: VX-745 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: VX-745 is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.