Certificate of Analysis

 

Product Name: VX-222
Catalog Number: M3512
CAS Number: 1026785-59-0

Physical and Chemical Properties
Formula: C25H35NO4S
Molecular Weight: 445.61
Solubility: DMSO 80 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: VX-222 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.