Certificate of Analysis

 

Catalog Number: M5343
Product Name: Voxtalisib Analogue
CAS Number: 1349796-36-6

Physical and Chemical Properties
Formula: C31H29N5O6S
Molecular Weight: 599.66
Solubility: 12 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Voxtalisib Analogue Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Voxtalisib (SAR245409, XL765) Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.