Certificate of Analysis

 

Catalog Number: M8962
Product Name: Voruciclib
CAS Number: 1000023-04-0

Physical and Chemical Properties
Formula: C22H19ClF3NO5
Molecular Weight: 469.84
Solubility: DMSO 30 μM
Long-term Storage: at -20°C
Chemical Structure: Voruciclib Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Voruciclib (P1446A-05) is a protein kinase inhibitor specific for the cyclin-dependent kinase 4 (CDK4) with IC50s of 90nM, 25nM, and 22nM for CDK4-CyclinD1, CDK1-Cyclin B, and CDK9-Cyclin T, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.