Certificate of Analysis

 

Product Name: Voruciclib
Catalog Number: M8962
CAS Number: 1000023-04-0

Physical and Chemical Properties
Formula: C22H19ClF3NO5
Molecular Weight: 469.84
Solubility: DMSO 30 μM
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Voruciclib Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Voruciclib (P1446A-05) is a protein kinase inhibitor specific for the cyclin-dependent kinase 4 (CDK4) with IC50s of 90nM, 25nM, and 22nM for CDK4-CyclinD1, CDK1-Cyclin B, and CDK9-Cyclin T, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.