Certificate of Analysis


Catalog Number: M6297
Product Name: Upadacitinib
CAS Number: 1310726-60-3

Physical and Chemical Properties
Formula: C17H19F3N6O
Molecular Weight: 380.37
Solubility: 22 mg/mL in DMSO
Storage: at -20°C
Chemical Structure: Upadacitinib Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Upadacitinib (ABT-494) is a potent and selective Janus kinase (JAK) 1 inhibitor being developed for the treatment of several autoimmune disorders with an IC50 of 43 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.