Certificate of Analysis

 

Product Name: Treprostinil sodium
Catalog Number: M20978
CAS Number: 289480-64-4

Physical and Chemical Properties
Formula: C23H33NaO5
Molecular Weight: 412.49
Solubility: DMSO 82 mg/mL; Water 82 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Treprostinil sodium Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a stabilized tricyclic analog of prostacyclin and a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively. Treprostinil promotes vasodilation and inhibits platelet aggregation in pulmonary and systemic arterial vascular beds, and can be used in studies related to pulmonary arterial hypertension (PAH).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.