Certificate of Analysis

 

Product Name: Tenalisib
Catalog Number: M7538
CAS Number: 1639417-53-0

Physical and Chemical Properties
Formula: C23H18FN5O2
Molecular Weight: 415.42
Solubility: 75 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Tenalisib Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: Tenalisib (RP6530) is a potent and selective dual PI3Kδ/γ inhibitor with IC50 values of 24.5 nM and 33.2 nM for PI3Kδ and PI3Kγ, respectively. Its selectivity over α and β isoforms are more than 300-fold and 100-fold, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.