Certificate of Analysis
| Product Name: | TCS-PIM-1-4a |
| Catalog Number: | M5019 |
| CAS Number: | 327033-36-3 |
Physical and Chemical Properties
| Formula: | C11H6F3NO2S |
| Molecular Weight: | 273.23 |
| Solubility: | DMSO ≥ 100 mg/mL Ethanol |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | TCS-PIM-1-4a is a Pim inhibitor that blocks mTORC1 activity via activation of AMPK; kills a wide range of both myeloid and lymphoid cell lines (with IC50 values ranging from 0.8 to 40 μM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |