Certificate of Analysis

 

Product Name: TCS PIM-1 1
Catalog Number: M3745
CAS Number: 491871-58-0

Physical and Chemical Properties
Formula: C18H11BrN2O2
Molecular Weight: 367.2
Solubility: DMSO 100 mM
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: TCS PIM-1 1 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s > 20,000 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.