Certificate of Analysis

 

Catalog Number: M3553
Product Name: TAK-285
CAS Number: 871026-44-7

Physical and Chemical Properties
Formula: C26H25ClF3N5O3
Molecular Weight: 547.96
Solubility: DMSO 100 mg/mL
Long-term Storage: at -20℃
Chemical Structure: TAK-285 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.