Certificate of Analysis

 

Catalog Number: M6293
Product Name: Tacrolimus monohydrate
CAS Number: 109581-93-3

Physical and Chemical Properties
Formula: C44H71NO13
Molecular Weight: 822.03
Solubility: 10 mM in DMSO
Long-term Storage: at -20°C
Chemical Structure: Tacrolimus monohydrate Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Tacrolimus monohydrate binds to FK506 binding protein (FKBP). This complex inhibits calcineurin phosphatase (PP2B). Tacrolimus monohydrate is a mTOR-independent autophagy inducer.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.