Certificate of Analysis

 

Product Name: SRT1720 Hydrochloride
Catalog Number: M1824
CAS Number: 1001645-58-4

Physical and Chemical Properties
Formula: C25H23N7OS.HCl
Molecular Weight: 506.02
Solubility: DMSO 26 mg/mL
Storage: -20°C, sealed
Chemical Structure: SRT1720 Hydrochloride Structure
Analytical Data
QC Standard: 100.0%
H-NMR: Consistent with structure
Product Information
Description: SRT1720 Hydrochloride is a selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol (EC1.5 = 0.16 versus 46.2 µM, respectively). SRT1720 increased the activity of SIRT1 and AMPKα phosphorylation at Ser485 via the cAMP-protein kinase A (PKA) pathway.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.