Certificate of Analysis

 

Product Name: SR-4835
Catalog Number: M10258
CAS Number: 2387704-62-1

Physical and Chemical Properties
Formula: C21H20Cl2N10O
Molecular Weight: 499.36
Solubility: DMSO ≥ 5 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SR-4835 Structure
Analytical Data
QC Standard: 98.74%
H-NMR: Consistent with structure
Product Information
Description: SR-4835 is a highly selective, dual inhibitor of CDK12 with IC50 values of 99 nM, Kd of 98 nM and CDK13 with Kd of 4.9 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.