Certificate of Analysis


Catalog Number: M5339
Product Name: SR 3677
CAS Number: 1072959-67-1

Physical and Chemical Properties
Formula: C22H24N4O4
Molecular Weight: 408.45
Solubility: 10mM in DMSO
Storage: at -20°C
Chemical Structure: SR 3677 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: SR-3677 is a new potent and selective ROCK-II inhibitor with an IC50 of ~3 nM in enzyme and cell based assays; IC50 for ROCK-I is 56 ± 12 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.