Certificate of Analysis

 

Catalog Number: M3026
Product Name: Sorafenib
CAS Number: 284461-73-0

Physical and Chemical Properties
Formula: C21H16ClF3N4O3
Molecular Weight: 464.82
Solubility: DMSO 60 mg/mL
Storage: at -20°C
Chemical Structure: Sorafenib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.