Certificate of Analysis


Catalog Number: M4865
Product Name: Smoothened Agonist (SAG) HCl
CAS Number: 912545-86-9(free base)

Physical and Chemical Properties
Formula: C28H29Cl2N3OS
Molecular Weight: 526.52
Solubility: DMSO 71 mg/mL;Water 100 mg/mL
Long-term Storage: at -20°C
Chemical Structure: Smoothened Agonist (SAG) HCl Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Smoothened Agonist (SAG) HCl is a cell-permeable Smoothened (Smo) agonist with EC50 of 3 nM in Shh-LIGHT2 cells.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.