Certificate of Analysis

 

Product Name: SMI-16a
Catalog Number: M9274
CAS Number: 587852-28-6

Physical and Chemical Properties
Formula: C13H13NO3S
Molecular Weight: 263.31
Solubility: DMSO: ≥ 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SMI-16a Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: SMI-16a is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases with IC50s of 150 nM and 20 nM against Pim-1 and Pim-2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.