Certificate of Analysis


Catalog Number: M1967
Product Name: Sitagliptin phosphate monohydrate
CAS Number: 654671-77-9

Physical and Chemical Properties
Formula: C16H15F6N5O.H3PO4.H2O
Molecular Weight: 523.32
Solubility: DMSO 100 mg/mL, Water 100 mg/mL
Long-term Storage: at -20°C
Chemical Structure: Sitagliptin phosphate monohydrate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Sitagliptin phosphate (MK-0431) is a potent inhibitor of dipeptidyl peptidase-4 (DPP-4) with IC50 of 19 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.