Certificate of Analysis

 

Product Name: Sitagliptin phosphate monohydrate
Catalog Number: M1967
CAS Number: 654671-77-9

Physical and Chemical Properties
Formula: C16H15F6N5O.H3PO4.H2O
Molecular Weight: 523.32
Solubility: Water 41 mg/mL; DMSO 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Sitagliptin phosphate monohydrate Structure
Analytical Data
QC Standard: 100.0%
H-NMR: Consistent with structure
Product Information
Description: Sitagliptin phosphate (MK-0431) is a potent inhibitor of dipeptidyl peptidase-4 (DPP-4) with IC50 of 19 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.