Certificate of Analysis

 

Catalog Number: M6175
Product Name: Serabelisib
CAS Number: 1268454-23-4

Physical and Chemical Properties
Formula: C19H17N5O3
Molecular Weight: 363.37
Solubility: 16 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Serabelisib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Serabelisib (INK-1117,MLN-1117,TAK-117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.