Certificate of Analysis

 

Product Name: SD-06
Catalog Number: M7558
CAS Number: 271576-80-8

Physical and Chemical Properties
Formula: C20H20ClN5O2
Molecular Weight: 397.86
Solubility: 10 mM in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SD-06  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po). IC50 value: 170 nM Target: p38MAPK
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.