Certificate of Analysis

 

Product Name: SB 239063
Catalog Number: M7582
CAS Number: 193551-21-2

Physical and Chemical Properties
Formula: C20H21FN4O2
Molecular Weight: 368.4
Solubility: 10 mM in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: SB 239063 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: SB 239063 is a potent and selective p38 MAPK inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.