Certificate of Analysis

 

Catalog Number: M3375
Product Name: S-(+)-Rolipram
CAS Number: 85416-73-5

Physical and Chemical Properties
Formula: C16H21NO3
Molecular Weight: 275.34
Solubility: DMSO 50 mg/mL
Long-term Storage: at -20℃
Chemical Structure: S-(+)-Rolipram Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.