Certificate of Analysis

 

Product Name: RP-6306
Catalog Number: M13388
CAS Number: 2719793-90-3

Physical and Chemical Properties
Formula: C18H20N4O2
Molecular Weight: 324.38
Form: Solid
Solubility: DMSO 50 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: RP-6306 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: RP-6306 is the first-in-class, highly potent and selective PKMYT1 inhibitor that preferentially kills tumor cells overexpressing CCNE1 and was shown to inhibit the growth of a broad range of CCNE1-amplified tumors in xenograft/PDX preclinical models, both as a single agent and in combination therapy settings.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.