Certificate of Analysis

 

Catalog Number: M5933
Product Name: Ripasudil (K-115) dihydrate
CAS Number: 887375-67-9

Physical and Chemical Properties
Formula: C15H23ClFN3O4S
Molecular Weight: 395.88
Solubility: 10 mM in DMSO
Long-term Storage: at -20℃
Chemical Structure: Ripasudil (K-115) dihydrate Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Ripasudil (K-115) hydrochloride dihydrate is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.