Certificate of Analysis

 

Product Name: RGLS4326
Catalog Number: M21511
CAS Number: 2229964-07-0

Physical and Chemical Properties
Formula: C95H115F3N32O51P8S8
Molecular Weight: 3082.42
Storage: -20°C, dry, sealed
Analytical Data
QC Standard: >97%
H-NMR: Consistent with structure
Product Information
Description: RGLS4326 (RG4326) is a first-in-class microRNA-17 (miR-17) oligonucleotide inhibitor. RGLS4326 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD). RGLS4326 acts on HeLa cells to inhibit the function of miR-17 with EC50 value of 28.3 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.