Certificate of Analysis

 

Catalog Number: M1669
Product Name: Regorafenib
CAS Number: 755037-03-7

Physical and Chemical Properties
Formula: C21H15ClF4N4O3
Molecular Weight: 482.82
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: Regorafenib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Regorafenib (BAY 73-4506) is a novel oral multikinase inhibitor of c-KIT, VEGFR2, B-Raf with IC50s of 17, 40 and 69 nM respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.