Certificate of Analysis

 

Catalog Number: M3633
Product Name: Refametinib
CAS Number: 923032-37-5

Physical and Chemical Properties
Formula: C19H20F3IN2O5S
Molecular Weight: 572.34
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: Refametinib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Refametinib (BAY 86-9766, RDEA119) is a potent, highly selective and ATP non-competitive inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.