Certificate of Analysis

 

Product Name: (Rac)-JBJ-04-125-02
Catalog Number: M11415
CAS Number: 2140807-05-0

Physical and Chemical Properties
Formula: C29H26FN5O3S
Molecular Weight: 543.61
Solubility: DMSO ≥ 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: (Rac)-JBJ-04-125-02  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: (Rac)-JBJ-04-125-02 is a racemate of JBJ-04-125-02, which is a potent, selectively mutated, allosteric and oral active EGFR inhibitor. The IC50 of EGFRL858R/T790M was 0.26 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.