Certificate of Analysis


Catalog Number: M2349
Product Name: (R)-Nepicastat hydrochloride
CAS Number: 195881-94-8

Physical and Chemical Properties
Formula: C14H15F2N3S.HCl
Molecular Weight: 331.81
Solubility: DMSO 50 mg/mL
Long-term Storage: at -20°C
Chemical Structure: (R)-Nepicastat hydrochloride Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: (R)-Nepicastat hydrochloride, the R-enantiomer of Nepicastat hydrochloride, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.