Certificate of Analysis

 

Catalog Number: M5031
Product Name: Poziotinib
CAS Number: 1092364-38-9

Physical and Chemical Properties
Formula: C23H21Cl2FN4O3
Molecular Weight: 491.34
Solubility: 10 mM in DMSO
Long-term Storage: at -20℃
Chemical Structure: Poziotinib Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Poziotinib(NOV120101; HM781-36B) is an irreversible Pan-HER inhibitor with IC50s of 3/5/23 nM for HER1/HER2/HER4 respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.