Certificate of Analysis

 

Catalog Number: M3218
Product Name: PKI-402
CAS Number: 1173204-81-3

Physical and Chemical Properties
Formula: C29H34N10O3
Molecular Weight: 570.65
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: PKI-402 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with IC50 of 2 nM/7 nM/16 nM/14 nM and 3 nM, respectively; also potent to PI3Kα mutants E545K and H1047R.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.