Certificate of Analysis

 

Catalog Number: M3552
Product Name: PHA-680632
CAS Number: 398493-79-3

Physical and Chemical Properties
Formula: C28H35N7O2
Molecular Weight: 501.62
Solubility: DMSO 90 mg/mL
Long-term Storage: at -20℃
Chemical Structure: PHA-680632 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.