Certificate of Analysis

 

Catalog Number: M2931
Product Name: PF-573228
CAS Number: 869288-64-2

Physical and Chemical Properties
Formula: C22H20F3N5O3S
Molecular Weight: 491.49
Solubility: DMSO 10 mg/mL
Long-term Storage: at -20℃
Chemical Structure: PF-573228 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.