Certificate of Analysis

 

Catalog Number: M2930
Product Name: PF-543
CAS Number: 1415562-82-1

Physical and Chemical Properties
Formula: C27H31NO4S
Molecular Weight: 465.6
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: PF-543 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.