Certificate of Analysis


Catalog Number: M1764
Product Name: PF-477736
CAS Number: 952021-60-2

Physical and Chemical Properties
Formula: C22H25N7O2
Molecular Weight: 419.48
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: PF-477736 Structure
Analytical Data
HPLC: Shows Min 99.21% purity
H-NMR: Consistent with structure
Product Information
Description: PF-477736 is a selective checkpoint kinase 1 (Chk1) inhibitor with Ki values of 0.49 nM and 47 nM for CHK1 and CHK2 respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.