Certificate of Analysis

 

Product Name: PF-06447475
Catalog Number: M3929
CAS Number: 1527473-33-1

Physical and Chemical Properties
Formula: C17H15N5O
Molecular Weight: 305.33
Solubility: DMSO 30 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: PF-06447475 Structure
Analytical Data
QC Standard: 99.42%
H-NMR: Consistent with structure
Product Information
Description: PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.