Certificate of Analysis

 

Catalog Number: M2927
Product Name: PF-04880594
CAS Number: 1111636-35-1

Physical and Chemical Properties
Formula: C19H16F2N8
Molecular Weight: 394.38
Solubility: DMSO
Long-term Storage: at -20℃
Chemical Structure: PF-04880594 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: PF-04880594 is a RAF inhibitor for BRAF/BRAFV599E and c-RAF with IC50 of 0.19 nM/0.13 nM and 0.39 nM, >100-fold selectivity over CSNK1, JNK2/3 and p38.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.