Certificate of Analysis

 

Catalog Number: M3286
Product Name: PF-00562271
CAS Number: 939791-38-5

Physical and Chemical Properties
Formula: C21H20F3N7O3S.C6H6O3S
Molecular Weight: 665.66
Solubility: DMSO 10 mg/mL
Long-term Storage: at -20℃
Chemical Structure: PF-00562271 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: PF-00562271 is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.