Certificate of Analysis
| Product Name: | Pexidartinib |
| Catalog Number: | M4867 |
| CAS Number: | 1029044-16-3 |
Physical and Chemical Properties
| Formula: | C20H15ClF3N5 |
| Molecular Weight: | 417.81 |
| Solubility: | DMSO 15 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.46% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Pexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit, and Flt3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |