Certificate of Analysis

 

Catalog Number: M9147
Product Name: Peficitinib
CAS Number: 944118-01-8

Physical and Chemical Properties
Formula: C18H22N4O2
Molecular Weight: 326.39
Solubility: DMSO: ≥ 55 mg/mL
Storage: at -20°C
Chemical Structure: Peficitinib Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.