Certificate of Analysis
| Product Name: | BMS202 |
| Catalog Number: | M5144 |
| CAS Number: | 1675203-84-5 |
Physical and Chemical Properties
| Formula: | C25H29N3O3 |
| Molecular Weight: | 419.52 |
| Solubility: | DMSO: ≥ 40 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.45% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Bms-202 is an effective non-peptide PD-1/PD-L complex inhibitor with IC50 of 18 nM and KD of 8 μM. Bms-202 directly binds to PD-L1 and blocks the human PD-1/PD-L interaction. Bms-202 has antitumor activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |