Certificate of Analysis

 

Catalog Number: M5863
Product Name: Pazopanib HCl (GW786034 )
CAS Number: 635702-64-6

Physical and Chemical Properties
Formula: C21H23N7O2S.HCl
Molecular Weight: 473.98
Solubility: 17 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Pazopanib HCl (GW786034 ) Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.