Certificate of Analysis


Catalog Number: M1821
Product Name: OSI-906
CAS Number: 867160-71-2

Physical and Chemical Properties
Formula: C26H23N5O
Molecular Weight: 421.49
Solubility: DMSO ≥84 mg/mL
Long-term Storage: at -20°C
Chemical Structure: OSI-906 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: OSI-906 (Linsitinib) is a potent, selective, dual ATP-competitive tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) with IC50 values of 35 nM and 75 nM respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.