Certificate of Analysis

 

Product Name: OSI-420
Catalog Number: M3491
CAS Number: 183320-51-6

Physical and Chemical Properties
Formula: C21H21N3O4.HCl
Molecular Weight: 415.87
Solubility: DMSO 80 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: OSI-420 Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.