Certificate of Analysis

 

Catalog Number: M2895
Product Name: Nutlin-3b
CAS Number: 675576-97-3

Physical and Chemical Properties
Formula: C30H30Cl2N4O4
Molecular Weight: 581.49
Solubility: DMSO 90 mg/mL
Long-term Storage: at -20℃
Chemical Structure: Nutlin-3b Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Nutlin-3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite enantiomer Nutlin-3a.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.