Certificate of Analysis

 

Product Name: NSC23766 trihydrochloride
Catalog Number: M2889
CAS Number: 1177865-17-6

Physical and Chemical Properties
Formula: C24H35N7.3HCl
Molecular Weight: 530.96
Solubility: Water: ≥ 25 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: NSC23766 trihydrochloride Structure
Analytical Data
QC Standard: 99.76%
H-NMR: Consistent with structure
Product Information
Description: NSC23766 3HCl is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM; does not inhibit the closely related targets, Cdc42 or RhoA.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.