Certificate of Analysis

 

Catalog Number: M5331
Product Name: Nintedanib (BIBF 1120)
CAS Number: 656247-17-5

Physical and Chemical Properties
Formula: C31H33N5O4
Molecular Weight: 539.62
Solubility: 6 mg/mL in DMSO
Long-term Storage: at -20℃
Chemical Structure: Nintedanib (BIBF 1120) Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.